Randomised controlled trial to determine the benefit of daily home-based exercise in addition to self-care in the management of breast cancer-related lymphoedema: a feasibility study.
Identifieur interne : 003237 ( Main/Exploration ); précédent : 003236; suivant : 003238Randomised controlled trial to determine the benefit of daily home-based exercise in addition to self-care in the management of breast cancer-related lymphoedema: a feasibility study.
Auteurs : Eunice Jeffs [Royaume-Uni] ; Theresa WisemanSource :
- Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer [ 1433-7339 ] ; 2013.
Descripteurs français
- KwdFr :
- MESH :
English descriptors
- KwdEn :
- MESH :
- geographic : England.
- complications : Breast Neoplasms.
- etiology : Lymphedema.
- methods : Exercise Therapy.
- therapy : Lymphedema.
- Aged, Arm, Confidence Intervals, Feasibility Studies, Female, Humans, Middle Aged, Self Care, Surveys and Questionnaires.
Abstract
Exercise is considered to be a key aspect of lymphoedema treatment, although there is little evidence for the therapeutic effect of exercise in managing breast cancer-related lymphoedema (BCRL). This small randomised controlled trial (RCT) was designed to determine the feasibility, prior to undertaking a larger RCT, of researching a daily home-based exercise programme to treat stable BCRL. An experimental design compared the exercise intervention combined with standard lymphoedema self-care to self-care alone over a 6-month period. Twenty-three women with stable unilateral BCRL of ≥10 % excess limb volume (ELV) were randomly allocated to a daily home-based exercise programme and self-care (n = 11) or self-care measures alone (n = 12). The primary objective was to determine difference in limb volume reduction for the two groups. Secondary objectives were to monitor change in other areas that impact BCRL: quality of life, arm function and range of shoulder movement. All 23 women completed the trial, providing full data for each time point. The intervention group showed a clinically and statistically significant improvement in relative ELV at week 26 (95 % confidence interval (CI) -26.57 to -5.12), whereas the control group improvement crossed the line of no effect (95 %CI -17.71 to 1.1). This study demonstrated the feasibility of conducting a RCT of exercise as a therapeutic intervention in the management of BCRL. Although the sample was small, the results support the findings of other exercise studies which have shown trends towards improvement.
DOI: 10.1007/s00520-012-1621-6
PubMed: 23073712
Affiliations:
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Theresa" uniqKey="Wiseman T" first="Theresa" last="Wiseman">Theresa Wiseman</name></author></analytic><series><title level="j">Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer</title><idno type="eISSN">1433-7339</idno><imprint><date when="2013" type="published">2013</date></imprint></series></biblStruct></sourceDesc></fileDesc><profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Aged</term><term>Arm</term><term>Breast Neoplasms (complications)</term><term>Confidence Intervals</term><term>England</term><term>Exercise Therapy (methods)</term><term>Feasibility Studies</term><term>Female</term><term>Humans</term><term>Lymphedema (etiology)</term><term>Lymphedema (therapy)</term><term>Middle Aged</term><term>Self Care</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="KwdFr" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Angleterre</term><term>Autosoins</term><term>Bras</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Humains</term><term>Intervalles de confiance</term><term>Lymphoedème ()</term><term>Lymphoedème (étiologie)</term><term>Sujet âgé</term><term>Traitement par les exercices physiques ()</term><term>Tumeurs du sein ()</term><term>Études de faisabilité</term></keywords><keywords scheme="MESH" type="geographic" xml:lang="en"><term>England</term></keywords><keywords scheme="MESH" qualifier="complications" xml:lang="en"><term>Breast Neoplasms</term></keywords><keywords scheme="MESH" qualifier="etiology" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Exercise Therapy</term></keywords><keywords scheme="MESH" qualifier="therapy" xml:lang="en"><term>Lymphedema</term></keywords><keywords scheme="MESH" qualifier="étiologie" xml:lang="fr"><term>Lymphoedème</term></keywords><keywords scheme="MESH" xml:lang="en"><term>Aged</term><term>Arm</term><term>Confidence Intervals</term><term>Feasibility Studies</term><term>Female</term><term>Humans</term><term>Middle Aged</term><term>Self Care</term><term>Surveys and Questionnaires</term></keywords><keywords scheme="MESH" xml:lang="fr"><term>Adulte d'âge moyen</term><term>Angleterre</term><term>Autosoins</term><term>Bras</term><term>Enquêtes et questionnaires</term><term>Femelle</term><term>Humains</term><term>Intervalles de confiance</term><term>Lymphoedème</term><term>Sujet âgé</term><term>Traitement par les exercices physiques</term><term>Tumeurs du sein</term><term>Études de faisabilité</term></keywords></textClass></profileDesc></teiHeader><front><div type="abstract" xml:lang="en">Exercise is considered to be a key aspect of lymphoedema treatment, although there is little evidence for the therapeutic effect of exercise in managing breast cancer-related lymphoedema (BCRL). This small randomised controlled trial (RCT) was designed to determine the feasibility, prior to undertaking a larger RCT, of researching a daily home-based exercise programme to treat stable BCRL. An experimental design compared the exercise intervention combined with standard lymphoedema self-care to self-care alone over a 6-month period. Twenty-three women with stable unilateral BCRL of ≥10 % excess limb volume (ELV) were randomly allocated to a daily home-based exercise programme and self-care (n = 11) or self-care measures alone (n = 12). The primary objective was to determine difference in limb volume reduction for the two groups. Secondary objectives were to monitor change in other areas that impact BCRL: quality of life, arm function and range of shoulder movement. All 23 women completed the trial, providing full data for each time point. The intervention group showed a clinically and statistically significant improvement in relative ELV at week 26 (95 % confidence interval (CI) -26.57 to -5.12), whereas the control group improvement crossed the line of no effect (95 %CI -17.71 to 1.1). This study demonstrated the feasibility of conducting a RCT of exercise as a therapeutic intervention in the management of BCRL. Although the sample was small, the results support the findings of other exercise studies which have shown trends towards improvement.</div></front></TEI><affiliations><list><country><li>Royaume-Uni</li></country></list><tree><noCountry><name sortKey="Wiseman, Theresa" sort="Wiseman, Theresa" uniqKey="Wiseman T" first="Theresa" last="Wiseman">Theresa Wiseman</name></noCountry><country name="Royaume-Uni"><noRegion><name sortKey="Jeffs, Eunice" sort="Jeffs, Eunice" uniqKey="Jeffs E" first="Eunice" last="Jeffs">Eunice Jeffs</name></noRegion></country></tree></affiliations></record>Pour manipuler ce document sous Unix (Dilib)
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